All of the 133 cardinals expected to take part in the secret conclave to elect a new pope have arrived in Rome, the Vatican said on Monday, with the race to succeed Pope Francis seen as wide open.

Beyond simply picking who the next pope will be, players and gamblers also can guess how many tries it will take the cardinals to choose the leader, which day of the week he’ll be elected, what new name he will decide on, or where his priorities will land on the progressive-conservative scale.

Two cardinals, Michael Czerny and Chibly Langlois, sat down with ABC News to discuss the challenges facing the church that the new pope will have to face.