Fingertip tactile neurons collectively encode the skin's viscoelastic state alongside current touch, potentially enabling the brain to better interpret forces during manipulation.

This valuable study concerns a model for transgenerational epigenetic inheritance, the learned avoidance by C. elegans of the PA14 pathogenic strain of Pseudomonas aeruginosa. A recent study ...

This important study investigates frequency-dependent effects of transcutaneous tibial nerve stimulation (TTNS) on bladder function in healthy humans and, through a computational model, shows that low ...

Caffeic acid phenethyl ester treats Clostridioides difficile infection by neutralizing Clostridioides difficile toxin B and altering the gut microbiota and metabolites.

This useful manuscript addresses a stability issue for long-term chronically implanted array recordings and electrolytic lesioning, which is relevant to both basic science and translational research.

Department of Pharmacology and Molecular Sciences, Johns Hopkins University, Baltimore, United States ...

This important study presents a compelling theoretical framework for understanding phase separation of membrane-bound proteins, with a focus on the organization of tight junction components. By ...

A dynamic DNA methylation 'barcode' on the X chromosome can distinguish thousands of individual adult male neurons and may record aspects of their development.

Nervous necrosis virus typically enters host cells via endocytosis, but it can also enter via a process called macropinocytosis.

This is a potentially valuable modeling study on sequence generation in the hippocampus in a variety of behavioral contexts. While the scope of the model is ambitious, its presentation is incomplete ...

This useful manuscript describes cryo-EM structures of archaeal proteasomes that reveal insights into how occupancy of binding pockets on the 20S protease regulates proteasome gating. The evidence ...

Experiments in mice reveal how three rare mutations in a gene called TRIO can lead to different neurodevelopmental outcomes.